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Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression

Bovine Neonatal Pancytopenia (BNP), a fatal bleeding syndrome of neonatal calves, is caused by maternal alloantibodies absorbed from colostrum and is characterized by lymphocytopenia, thrombocytopenia and bone marrow hypoplasia. An inactivated viral vaccine is the likely source of alloantigens induc...

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Publicado no:Sci Rep
Main Authors: Benedictus, Lindert, Luteijn, Rutger D., Otten, Henny, Jan Lebbink, Robert, van Kooten, Peter J. S., Wiertz, Emmanuel J. H. J., Rutten, Victor P. M. G., Koets, Ad P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522679/
https://ncbi.nlm.nih.gov/pubmed/26235972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12748
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