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BCRP and P-gp relay overexpression in triple negative basal-like breast cancer cell line: a prospective role in resistance to Olaparib

The triple negative basal-like (TNBL) breast carcinoma is an aggressive and unfavorable prognosis disease. Inhibitors of poly(ADP-ribose) polymerase such as Olaparib could represent a promising targeted therapy but their sensitivity against Multidrug Resistance proteins (MDR), which causes resistanc...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Dufour, Robin, Daumar, Pierre, Mounetou, Emmanuelle, Aubel, Corinne, Kwiatkowski, Fabrice, Abrial, Catherine, Vatoux, Catherine, Penault-Llorca, Frédérique, Bamdad, Mahchid
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522660/
https://ncbi.nlm.nih.gov/pubmed/26234720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12670
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