Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling

In drug discovery, prediction of selectivity and toxicity require the evaluation of cellular calcium homeostasis. The rat is a preferred laboratory animal for pharmacology and toxicology studies, while currently no calcium indicator protein expressing rat model is available. We established a transge...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Szebényi, Kornélia, Füredi, András, Kolacsek, Orsolya, Pergel, Enikő, Bősze, Zsuzsanna, Bender, Balázs, Vajdovich, Péter, Tóvári, József, Homolya, László, Szakács, Gergely, Héja, László, Enyedi, Ágnes, Sarkadi, Balázs, Apáti, Ágota, Orbán, Tamás I.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522653/
https://ncbi.nlm.nih.gov/pubmed/26234466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12645
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker