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Excision Efficiency Is Not Strongly Coupled to Transgenic Rate: Cell Type-Dependent Transposition Efficiency of Sleeping Beauty and piggyBac DNA Transposons

The Sleeping Beauty (SB) and piggyBac (PB) DNA transposons represent an emerging new gene delivery technology, potentially suitable for human gene therapy applications. Previous studies pointed to important differences between these transposon systems, depending on the cell types examined and the me...

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Detalhes bibliográficos
Main Authors: Kolacsek, Orsolya, Erdei, Zsuzsa, Apáti, Ágota, Sándor, Sára, Izsvák, Zsuzsanna, Ivics, Zoltán, Sarkadi, Balázs, Orbán, Tamás I.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142840/
https://ncbi.nlm.nih.gov/pubmed/25045962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2013.149
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