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Identification of a heritable deficiency of the folate-dependent enzyme 10-formyltetrahydrofolate dehydrogenase in mice.

During the analysis of liver protein expression in the offspring of male mice irradiated with fission-spectrum neutrons, one offspring displayed a heritable 50% decrease in the abundance of two proteins. Homozygous mice lacking detectable quantities of these proteins were obtained through breeding....

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Champion, K M, Cook, R J, Tollaksen, S L, Giometti, C S
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45226/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7972060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.24.11338
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