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Human embryonic lung fibroblasts treated with artesunate exhibit reduced rates of proliferation and human cytomegalovirus infection in vitro

BACKGROUND: Cytomegalovirus (CMV) pneumonia is a major cause of death in immunosuppressed patients. Despite the effective treatment with ganciclovir (GCV) and other antiviral agents, the mortality rate remains between 30% to 50%. Recently, the anti-malarial drug artesunate (ART) wasfound to exhibit...

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Zeng, Ai-Hong, Ou, Yang-Ying, Guo, Ming-Ming, Dai, Xuan, Zhou, De-Zhi, Chen, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522492/
https://ncbi.nlm.nih.gov/pubmed/26380730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2072-1439.2015.07.05
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