Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like properties

In the search for effective therapeutic strategies, protein-based biologicals are under intense development. While monoclonal antibodies represent the majority of these drugs, other innovative approaches are exploring the use of scaffold proteins for the creation of binding molecules with tailor-mad...

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Détails bibliographiques
Publié dans:FEBS Open Bio
Auteurs principaux: Job, Florian, Settele, Florian, Lorey, Susan, Rundfeldt, Chris, Baumann, Lars, Beck-Sickinger, Annette G., Haupts, Ulrich, Lilie, Hauke, Bosse-Doenecke, Eva
Format: Artigo
Langue:Inglês
Publié: Elsevier 2015
Sujets:
Research article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522466/
https://ncbi.nlm.nih.gov/pubmed/26258013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.07.002
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