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Nuclear membrane diversity: underlying tissue-specific pathologies in disease?
Human ‘laminopathy’ diseases result from mutations in genes encoding nuclear lamins or nuclear envelope (NE) transmembrane proteins (NETs). These diseases present a seeming paradox: the mutated proteins are widely expressed yet pathology is limited to specific tissues. New findings suggest tissue-sp...
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| Publicado no: | Curr Opin Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522394/ https://ncbi.nlm.nih.gov/pubmed/26115475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2015.06.003 |
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