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Cytokine Profiling of Ascites at Primary Surgery Identifies an Interaction of Tumor Necrosis Factor-α and Interleukin-6 in Predicting Reduced Progression-Free Survival in Epithelial Ovarian Cancer

OBJECTIVES: Epithelial ovarian cancer (EOC) typically presents with advanced disease. Even with optimal debulking and response to adjuvant chemotherapy, the majority of patients will have disease relapse. We evaluated cytokine and chemokine profiles in ascites at primary surgery as biomarkers for pr...

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Détails bibliographiques
Publié dans:Gynecol Oncol
Auteurs principaux: Kolomeyevskaya, Nonna, Eng, Kevin H., Khan, Anm Nazmul H., Grzankowski, Kassondra S., Singel, Kelly L., Moysich, Kirsten, Segal, Brahm H.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522366/
https://ncbi.nlm.nih.gov/pubmed/26001328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.05.009
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