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Simultaneous assessment of NF-κB/p65 phosphorylation and nuclear localization using imaging flow cytometry

Aberrant activity of Nuclear Factor–kappaB (NF-κB) is associated with many diseases and is therapeutically targeted. Post-translational modifications, particularly phosphorylation of the RELA/p65 sub-unit, are essential for cytoplasmic to nuclear localization of NF-κB/p65 and initiation of transcrip...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Maguire, Orla, O'Loughlin, Kieran, Minderman, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522232/
https://ncbi.nlm.nih.gov/pubmed/25862606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2015.03.018
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