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Underexpression of the 43 kDa inositol polyphosphate 5-phosphatase is associated with cellular transformation.

The 43 kDa inositol polyphosphate 5-phosphatase (5-phosphatase) hydrolyses the second messenger molecules inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] and inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4,5)P4]. We have underexpressed the 43 kDa 5-phosphatase by stably transfecting normal rat kidney cell...

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Pubblicato in:EMBO J
Autori principali: Speed, C J, Little, P J, Hayman, J A, Mitchell, C A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452223/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8890159/
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