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The Role of Aromaticity, Hybridization, Electrostatics, and Covalency in Resonance-Assisted Hydrogen Bonds of Adenine–Thymine (AT) Base Pairs and Their Mimics

Hydrogen bonds play a crucial role in many biochemical processes and in supramolecular chemistry. In this study, we show quantum chemically that neither aromaticity nor other forms of π assistance are responsible for the enhanced stability of the hydrogen bonds in adenine–thymine (AT) DNA base pairs...

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Publicat a:ChemistryOpen
Autors principals: Guillaumes, L, Simon, S, Fonseca Guerra, C
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522182/
https://ncbi.nlm.nih.gov/pubmed/26246994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402132
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