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Cytidine-5-diphosphocholine reduces microvascular permeability during experimental endotoxemia

BACKGROUND: Microvascular permeability and leukocyte adhesion are pivotal mechanisms in sepsis pathophysiology contributing to the development of shock and mortality. No effective pharmacological therapy is currently available to restore microvascular barrier function in sepsis. Cholinergic mediator...

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Bibliografiske detaljer
Udgivet i:BMC Anesthesiol
Main Authors: Schmidt, Karsten, Hernekamp, Jochen Frederick, Doerr, Miriam, Zivkovic, Aleksandar R., Brenner, Thorsten, Walther, Andreas, Weigand, Markus A., Hofer, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522138/
https://ncbi.nlm.nih.gov/pubmed/26232247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-015-0086-9
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