Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in Plasmodium falciparum

BACKGROUND: The 175-kDa erythrocyte binding antigen (EBA-175) of Plasmodium falciparum plays a crucial role in merozoite invasion into human erythrocytes. EBA-175 is believed to have been under diversifying selection; however, there have been no studies investigating the effect of dispersal of human...

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Vydáno v:Malar J
Hlavní autoři: Yasukochi, Yoshiki, Naka, Izumi, Patarapotikul, Jintana, Hananantachai, Hathairad, Ohashi, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522064/
https://ncbi.nlm.nih.gov/pubmed/26231699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0820-2
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