Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in Plasmodium falciparum

BACKGROUND: The 175-kDa erythrocyte binding antigen (EBA-175) of Plasmodium falciparum plays a crucial role in merozoite invasion into human erythrocytes. EBA-175 is believed to have been under diversifying selection; however, there have been no studies investigating the effect of dispersal of human...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Malar J
Main Authors: Yasukochi, Yoshiki, Naka, Izumi, Patarapotikul, Jintana, Hananantachai, Hathairad, Ohashi, Jun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522064/
https://ncbi.nlm.nih.gov/pubmed/26231699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0820-2
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