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Remodeling the chromatin structure of a nucleosome array by transcription factor-targeted trans-displacement of histones.

To investigate mechanisms of chromatin remodeling, we have examined the fate of a single nucleosome core within a spaced nucleosome array upon the binding of transcription factors. GAL4 binding to this nucleosome within an array resulted in the establishment of DNase I hypersensitivity adjacent to t...

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Autori principali: Owen-Hughes, T, Workman, J L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC452202/
https://ncbi.nlm.nih.gov/pubmed/8887561
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