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Chemical shift guided homology modeling of larger proteins
We describe an alternate approach to protein structure determination that relies on experimental NMR chemical shifts, plus sparse NOEs if available. The newly introduced alignment method, POMONA, directly exploits the powerful bioinformatics algorithms previously developed for sequence-based homolog...
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| Publié dans: | Nat Methods |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521993/ https://ncbi.nlm.nih.gov/pubmed/26053889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3437 |
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