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Protein structure determination by combining sparse NMR data with evolutionary couplings

Accurate protein structure determination by NMR is challenging for larger proteins, for which experimental data is often incomplete and ambiguous. Fortunately, the upsurge in evolutionary sequence information and advances in maximum entropy statistical methods now provide a rich complementary source...

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Bibliografiske detaljer
Udgivet i:Nat Methods
Main Authors: Tang, Yuefeng, Huang, Yuanpeng Janet, Hopf, Thomas A., Sander, Chris, Marks, Debora S., Montelione, Gaetano T.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521990/
https://ncbi.nlm.nih.gov/pubmed/26121406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3455
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