Critical roles for WDR72 in calcium transport and matrix protein removal during enamel maturation

Defects in WDR72 (WD repeat-containing protein 72) cause autosomal recessive hypomaturation amelogenesis imperfecta. We generated and characterized Wdr72-knockout/lacZ-knockin mice to investigate the role of WDR72 in enamel formation. In all analyses, enamel formed by Wdr72 heterozygous mice was ind...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Wang, Shih-Kai, Hu, Yuanyuan, Yang, Jie, Smith, Charles E, Nunez, Stephanie M, Richardson, Amelia S, Pal, Soumya, Samann, Andrew C, Hu, Jan C-C, Simmer, James P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521966/
https://ncbi.nlm.nih.gov/pubmed/26247047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.143
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