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Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer

BACKGROUND: In lung cancer, uPA, its receptor (uPAR), and the inhibitors PAI-1 and PAI-2 of the plasminogen activator family interact with MMP-2 and MMP-9 of the MMP family to promote cancer progression. However, it remains undetermined which of these markers plays the most important role and may be...

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Pubblicato in:PLoS One
Autori principali: Su, Chia-Yi, Liu, Yu-Peng, Yang, Chih-Jen, Lin, Yuan-Feng, Chiou, Jean, Chi, Li-Hsing, Lee, Jih-Jong, Wu, Alex T. H., Lu, Pei-Jung, Huang, Ming-Shyan, Hsiao, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521958/
https://ncbi.nlm.nih.gov/pubmed/26230665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133411
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