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FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2.

Fibroblast growth factor (FGF) activates a protein kinase cascade in SK-N-MC cells that regulates gene expression at a cyclic-AMP response element (CRE) by stimulating the transcriptional activity of CREB. The activation of CREB is prevented by a dominant negative mutant of Ras and triggered via the...

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Udgivet i:EMBO J
Principais autores: Tan, Y, Rouse, J, Zhang, A, Cariati, S, Cohen, P, Comb, M J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8887554/
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