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A Single RNaseIII Domain Protein from Entamoeba histolytica Has dsRNA Cleavage Activity and Can Help Mediate RNAi Gene Silencing in a Heterologous System

Dicer enzymes process double-stranded RNA (dsRNA) into small RNAs that target gene silencing through the RNA interference (RNAi) pathway. Dicer enzymes are complex, multi-domain RNaseIII proteins, however structural minimalism of this protein has recently emerged in parasitic and fungal systems. The...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pompey, Justine M., Foda, Bardees, Singh, Upinder
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521922/
https://ncbi.nlm.nih.gov/pubmed/26230096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133740
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