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Identification and Validation of Protein Biomarkers of Response to Neoadjuvant Platinum Chemotherapy in Muscle Invasive Urothelial Carcinoma

BACKGROUND: The 5-year cancer specific survival (CSS) for patients with muscle invasive urothelial carcinoma of the bladder (MIBC) treated with cystectomy alone is approximately 50%. Platinum based neoadjuvant chemotherapy (NAC) plus cystectomy results in a marginal 5-10% increase in 5-year CSS in M...

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Udgivet i:PLoS One
Main Authors: Baras, Alexander S., Gandhi, Nilay, Munari, Enrico, Faraj, Sheila, Shultz, Luciana, Marchionni, Luigi, Schoenberg, Mark, Hahn, Noah, Hoque, Mohammad, Berman, David, Bivalacqua, Trinity J., Netto, George
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521868/
https://ncbi.nlm.nih.gov/pubmed/26230923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131245
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