The Effects of Xanthine Oxidoreductase Inhibitors on Oxidative Stress Markers following Global Brain Ischemia Reperfusion Injury in C57BL/6 Mice

We demonstrated that 3-nitrotyrosine and 4-hydroxy-2-nonenal levels in mouse brain were elevated from 1 h until 8 h after global brain ischemia for 14 min induced with the 3-vessel occlusion model; this result indicates that ischemia reperfusion injury generated oxidative stress. Reactive oxygen spe...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yamaguchi, Masahiro, Okamoto, Ken, Kusano, Teruo, Matsuda, Yoko, Suzuki, Go, Fuse, Akira, Yokota, Hiroyuki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521791/
https://ncbi.nlm.nih.gov/pubmed/26230326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133980
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