Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1

Wnt/beta-catenin signaling plays a central role in guiding the differentiation of the posterior parts of the primitive gut tube into intestinal structures in vivo and some studies suggest that FGF4 is another crucial factor for intestinal development. The aim of this study was to define the effects...

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Опубликовано в: :PLoS One
Главные авторы: Tamminen, Kaisa, Balboa, Diego, Toivonen, Sanna, Pakarinen, Mikko P., Wiener, Zoltan, Alitalo, Kari, Otonkoski, Timo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521699/
https://ncbi.nlm.nih.gov/pubmed/26230325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134551
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