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Ultrasound effects on brain-targeting mannosylated liposomes: in vitro and blood–brain barrier transport investigations

Delivering drugs to intracerebral regions can be accomplished by improving the capacity of transport through blood–brain barrier. Using sertraline as model drug for brain targeting, the current study aimed at modifying its liposomal vesicles with mannopyranoside. Box-Behnken design was employed to s...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Zidan, Ahmed S, Aldawsari, Hibah
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521675/
https://ncbi.nlm.nih.gov/pubmed/26244012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S87906
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