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Measuring windows of selection for anti-malarial drug treatments

BACKGROUND: The long half-lives of malaria ‘partner’ drugs are a potent force selecting for drug resistance. Clinical trials can quantify this effect by estimating a window of selection (WoS), defined as the amount of time post-treatment when drug levels are sufficiently high that resistant parasite...

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Dades bibliogràfiques
Publicat a:Malar J
Autors principals: Kay, Katherine, Hastings, Ian M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521485/
https://ncbi.nlm.nih.gov/pubmed/26228915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0810-4
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