DNA methylation levels are highly correlated between pooled samples and averaged values when analysed using the Infinium HumanMethylation450 BeadChip array

BACKGROUND: DNA methylation is a heritable and stable epigenetic mark implicated in complex human traits. Epigenome-wide association studies (EWAS) using array-based technology are becoming widely used to identify differentially methylated sites associated with complex diseases. EWAS studies require...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Gallego-Fabrega, Cristina, Carrera, Caty, Muiño, Elena, Montaner, Joan, Krupinski, Jurek, Fernandez-Cadenas, Israel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Methodology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521379/
https://ncbi.nlm.nih.gov/pubmed/26236407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0097-x
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