Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis

INTRODUCTION: Transforming growth factor (TGF)-β and interleukin (IL)-13 play a crucial role in the pathogenesis of systemic sclerosis (SSc), partly through activation of collagen production that leads to fibrosis. The aim of the present study was to determine whether TFG-β alters IL-13 production i...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Baraut, Julie, Farge, Dominique, Jean-Louis, Francette, Masse, Ingrid, Grigore, Elena Ivan, Arruda, Lucas C. M., Lamartine, Jérôme, Verrecchia, Franck, Michel, Laurence
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521372/
https://ncbi.nlm.nih.gov/pubmed/26227022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0708-0
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