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dissectHMMER: a HMMER-based score dissection framework that statistically evaluates fold-critical sequence segments for domain fold similarity

BACKGROUND: Annotation transfer for function and structure within the sequence homology concept essentially requires protein sequence similarity for the secondary structural blocks forming the fold of a protein. A simplistic similarity approach in the case of non-globular segments (coiled coils, low...

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Publicat a:Biol Direct
Autors principals: Wong, Wing-Cheong, Yap, Choon-Kong, Eisenhaber, Birgit, Eisenhaber, Frank
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521371/
https://ncbi.nlm.nih.gov/pubmed/26228544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0068-3
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