The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse.
Homozygosity for a null mutation in the scl gene causes mid-gestational embryonic lethality in the mouse due to failure of development of primitive hematopoiesis. Whilst this observation established the role of the scl gene product in primitive hematopoiesis, the death of the scl null embryos preclu...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452135/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8861941/ |
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