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Simultaneously targeting inflammatory response and parasite sequestration in brain to treat Experimental Cerebral Malaria

Malaria afflicts around 200 million people annually, with a mortality number close to 600,000. The mortality rate in Human Cerebral Malaria (HCM) is unacceptably high (15–20%), despite the availability of artemisinin-based therapy. An effective adjunct therapy is urgently needed. Experimental Cerebr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dende, Chaitanya, Meena, Jairam, Nagarajan, Perumal, Panda, Amulya K., Rangarajan, Pundi N., Padmanaban, Govindarajan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521148/
https://ncbi.nlm.nih.gov/pubmed/26227888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12671
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