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Axonal protection by brimonidine with modulation of p62 expression in TNF-induced optic nerve degeneration

PURPOSE: The p62, also called sequestosome 1 (SQSTM1), plays a crucial role in tumor necrosis factor (TNF)-induced optic nerve degeneration. Brimonidine has been shown to have protective effects on retinal ganglion cell bodies, although its role in their axons remains to be examined. We determined w...

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Dades bibliogràfiques
Publicat a:Graefes Arch Clin Exp Ophthalmol
Autors principals: Kitaoka, Yasushi, Kojima, Kaori, Munemasa, Yasunari, Sase, Kana, Takagi, Hitoshi
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521096/
https://ncbi.nlm.nih.gov/pubmed/25863674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00417-015-3005-3
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