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Absence of the Regulator of G-protein Signaling, RGS4, Predisposes to Atrial Fibrillation and Is Associated with Abnormal Calcium Handling

The description of potential molecular substrates for predisposition to atrial fibrillation (AF) is incomplete, and it is unknown what role regulators of G-protein signaling might play. We address whether the attenuation of RGS4 function may promote AF and the mechanism through which this occurs. Fo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Opel, Aaisha, Nobles, Muriel, Montaigne, David, Finlay, Malcolm, Anderson, Naomi, Breckenridge, Ross, Tinker, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521044/
https://ncbi.nlm.nih.gov/pubmed/26088132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666719
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