Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha.

A functional approach of gene cloning was applied to HeLa cells in an attempt to isolate positive mediators of programmed cell death. The approach was based on random inactivation of genes by transfections with antisense cDNA expression libraries, followed by the selection of cells that survived in...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Deiss, L P, Galinka, H, Berissi, H, Cohen, O, Kimchi, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670891/
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