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Evaluation of Biomarkers of Oxidative Stress and Apoptosis in Patients with Severe Methotrexate Neurotoxicity: A Case Series

Central nervous system (CNS) treatment is an essential part of ALL therapy and the most common CNS treatment is intrathecal (IT) and high-dose intravenous (IV) methotrexate (MTX). Treatment with MTX may cause neurotoxicity, which is often accompanied by neurologic changes, delays in treatment, and p...

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Detalhes bibliográficos
Publicado no:J Pediatr Oncol Nurs
Main Authors: Taylor, Olga A., Hockenberry, Marilyn J., McCarthy, Kathy, Gundy, Patricia, Montgomery, David, Ross, Adam, Scheurer, Michael E., Moore, Ida M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520788/
https://ncbi.nlm.nih.gov/pubmed/25637187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1043454214563409
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