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A method to predict the impact of regulatory variants from DNA sequence
Most variants implicated in common human disease by Genome-Wide Association Studies (GWAS) lie in non-coding sequence intervals. Despite the suggestion that regulatory element disruption represents a common theme, identifying causal risk variants within indicted genomic regions remains a significant...
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| Publicado no: | Nat Genet |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520745/ https://ncbi.nlm.nih.gov/pubmed/26075791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3331 |
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