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Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.

Bruton tyrosine kinase (Btk) has been implicated as the defective gene in both human and murine B-cell deficiencies. The identification of molecules that interact with Btk may shed light on critical processes in lymphocyte development. The N-terminal unique region of Btk contains a pleckstrin homolo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsukada, S, Simon, M I, Witte, O N, Katz, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC45206/
https://ncbi.nlm.nih.gov/pubmed/7972043
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