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Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection

Dengue virus (DV) infection is the most prevalent mosquito-borne viral disease and its manifestation has been shown to be contributed in part by the host immune responses. In this study, pathogen recognition receptors, Toll-like receptor (TLR) 2 and TLR6 were found to be up-regulated in DV-infected...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Chen, Jincheng, Ng, Mary Mah-Lee, Chu, Justin Jang Hann
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520596/
https://ncbi.nlm.nih.gov/pubmed/26226614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005053
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