Monitoring the Activation of the DNA Damage Response Pathway in a 3D Spheroid Model

Monitoring the DNA-Damage Response (DDR) activated pathway in multicellular tumor spheroid models is an important challenge as these 3D models have demonstrated their major relevance in pharmacological evaluation. Herein we present DDR-Act-FP, a fluorescent biosensor that allows detection of DDR act...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Mondesert, Odile, Frongia, Céline, Clayton, Olivia, Boizeau, Marie-Laure, Lobjois, Valérie, Ducommun, Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520595/
https://ncbi.nlm.nih.gov/pubmed/26225756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134411
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