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Monitoring the Activation of the DNA Damage Response Pathway in a 3D Spheroid Model
Monitoring the DNA-Damage Response (DDR) activated pathway in multicellular tumor spheroid models is an important challenge as these 3D models have demonstrated their major relevance in pharmacological evaluation. Herein we present DDR-Act-FP, a fluorescent biosensor that allows detection of DDR act...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520595/ https://ncbi.nlm.nih.gov/pubmed/26225756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134411 |
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