All-Trans Retinoic Acid Induces TGF-β(2) in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2

OBJECTIVE: We have shown previously that preterm infants are at risk of necrotizing enterocolitis (NEC), an inflammatory bowel necrosis typically seen in infants born prior to 32 weeks’ gestation, because of the developmental deficiency of transforming growth factor (TGF)-β(2) in the intestine. The...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Namachivayam, Kopperuncholan, MohanKumar, Krishnan, Arbach, Dima, Jagadeeswaran, Ramasamy, Jain, Sunil K., Natarajan, Viswanathan, Mehta, Dolly, Jankov, Robert P., Maheshwari, Akhil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520553/
https://ncbi.nlm.nih.gov/pubmed/26225425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134003
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