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All-Trans Retinoic Acid Induces TGF-β(2) in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2

OBJECTIVE: We have shown previously that preterm infants are at risk of necrotizing enterocolitis (NEC), an inflammatory bowel necrosis typically seen in infants born prior to 32 weeks’ gestation, because of the developmental deficiency of transforming growth factor (TGF)-β(2) in the intestine. The...

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Vydáno v:	PLoS One
Hlavní autoři:	Namachivayam, Kopperuncholan, MohanKumar, Krishnan, Arbach, Dima, Jagadeeswaran, Ramasamy, Jain, Sunil K., Natarajan, Viswanathan, Mehta, Dolly, Jankov, Robert P., Maheshwari, Akhil
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science 2015
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4520553/ https://ncbi.nlm.nih.gov/pubmed/26225425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134003
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All-Trans Retinoic Acid Induces TGF-β(2) in Intestinal Epithelial Cells via RhoA- and p38α MAPK-Mediated Activation of the Transcription Factor ATF2

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