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High Prevalence of Pre-invasive Lesions Adjacent to BRCA1/2-Associated Breast Cancers

PURPOSE: Mutations in BRCA1 and BRCA2 increase a woman's lifetime risk of developing breast cancer to 43%-84%. It was originally postulated that BRCA1/2-associated breast cancers develop more rapidly than sporadic cancers and may lack pre-invasive lesions. More recent studies have found pre-inv...

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Vydáno v:Cancer Prev Res (Phila)
Hlavní autoři: Arun, Banu, Vogel, Kristen J., Lopez, Adriana, Hernandez, Mike, Atchley, Deann, Broglio, Kristine R., Amos, Christopher I., Meric-Bernstam, Funda, Kuerer, Henry, Hortobagyi, Gabriel N., Albarracin, Constance T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520422/
https://ncbi.nlm.nih.gov/pubmed/19174581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0050
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