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Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element.

The tax gene product of the type I human T-cell leukemia virus (HTLV-I) is a potent transcriptional activator of various growth-related cellular genes, including that encoding interleukin-2 (IL-2). Tax activation of many of these target genes appears to be mediated by the NF-kappa B/Rel and CREB/ATF...

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Библиографические подробности
Главные авторы: Good, L, Maggirwar, S B, Sun, S C
Формат: Artigo
Язык:Inglês
Опубликовано: 1996
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC452042/
https://ncbi.nlm.nih.gov/pubmed/8670878
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