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Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postmitotic neurons
AIM: In nondividing neurons examine the role of Gadd45b in active 5-methylcytosine (5MC) and 5-hydroxymethylcytosine (5HMC) removal at a gene promoter highly implicated in mental illnesses and cognition, Bdnf. MATERIALS & METHODS: Mouse primary cortical neuronal cultures with and without Gadd45b...
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| Veröffentlicht in: | Epigenomics |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4520229/ https://ncbi.nlm.nih.gov/pubmed/26111030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.15.12 |
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