Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression

The transition of AKI to CKD has major clinical significance. As reviewed here, recent studies show that a subpopulation of dedifferentiated, proliferating tubules recovering from AKI undergo pathologic growth arrest, fail to redifferentiate, and become atrophic. These abnormal tubules exhibit persi...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Venkatachalam, Manjeri A., Weinberg, Joel M., Kriz, Wilhelm, Bidani, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2015
Fag:
Up Front Matters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520181/
https://ncbi.nlm.nih.gov/pubmed/25810494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015010006
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