Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca(2+) Channel in Renal Fibrosis

Transient receptor potential canonical (TRPC) Ca(2+)-permeant channels, especially TRPC3, are increasingly implicated in cardiorenal diseases. We studied the possible role of fibroblast TRPC3 in the development of renal fibrosis. In vitro, a macromolecular complex formed by TRPC1/TRPC3/TRPC6 existed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Soc Nephrol
Prif Awduron: Saliba, Youakim, Karam, Ralph, Smayra, Viviane, Aftimos, Georges, Abramowitz, Joel, Birnbaumer, Lutz, Farès, Nassim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2015
Pynciau:
Basic Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520158/
https://ncbi.nlm.nih.gov/pubmed/25479966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014010065
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