Understanding Xeroderma Pigmentosum Complementation Groups Using Gene Expression Profiling after UV-Light Exposure

Children with the recessive genetic disorder Xeroderma Pigmentosum (XP) have extreme sensitivity to UV-light, a 10,000-fold increase in skin cancers from age 2 and rarely live beyond 30 years. There are seven genetic subgroups of XP, which are all resultant of pathogenic mutations in genes in the nu...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Bowden, Nikola A., Beveridge, Natalie J., Ashton, Katie A., Baines, Katherine J., Scott, Rodney J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2015
Ämnen:
Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519934/
https://ncbi.nlm.nih.gov/pubmed/26184184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160715985
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