Protective Immunity and Reduced Renal Colonization Induced by Vaccines Containing Recombinant Leptospira interrogans Outer Membrane Proteins and Flagellin Adjuvant

Leptospirosis is a global zoonotic disease caused by different Leptospira species, such as Leptospira interrogans, that colonize the renal tubules of wild and domestic animals. Thus far, attempts to develop effective leptospirosis vaccines, both for humans and animals, have failed to induce immune r...

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Detalles Bibliográficos
Publicado en:Clin Vaccine Immunol
Autores principales: Monaris, D., Sbrogio-Almeida, M. E., Dib, C. C., Canhamero, T. A., Souza, G. O., Vasconcellos, S. A., Ferreira, L. C. S., Abreu, P. A. E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519722/
https://ncbi.nlm.nih.gov/pubmed/26108285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00285-15
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