Protective Immunity and Reduced Renal Colonization Induced by Vaccines Containing Recombinant Leptospira interrogans Outer Membrane Proteins and Flagellin Adjuvant

Leptospirosis is a global zoonotic disease caused by different Leptospira species, such as Leptospira interrogans, that colonize the renal tubules of wild and domestic animals. Thus far, attempts to develop effective leptospirosis vaccines, both for humans and animals, have failed to induce immune r...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Vaccine Immunol
Hauptverfasser: Monaris, D., Sbrogio-Almeida, M. E., Dib, C. C., Canhamero, T. A., Souza, G. O., Vasconcellos, S. A., Ferreira, L. C. S., Abreu, P. A. E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519722/
https://ncbi.nlm.nih.gov/pubmed/26108285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00285-15
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