Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation.

Lignende værker

• The activation process of the α(1B)-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
  af: Scheer, Alexander, et al.
  Udgivet: (1997)
• A constitutively active mutant of the alpha 1B-adrenergic receptor can cause greater agonist-dependent down-regulation of the G-proteins G9 alpha and G11 alpha than the wild-type receptor.
  af: Lee, T W, et al.
  Udgivet: (1996)
• G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity.
  af: Allen, L F, et al.
  Udgivet: (1991)
• A constitutively active mutant beta 2-adrenergic receptor is constitutively desensitized and phosphorylated.
  af: Pei, G, et al.
  Udgivet: (1994)
• Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the β(2)-adrenergic receptor
  af: Carmine, Renata Del, et al.
  Udgivet: (2002)