Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1

BACKGROUND: No opioid receptor, mu 1 (OPRM1) gene polymorphisms, including the functional single nucleotide polymorphism (SNP) rs1799971, have been conclusively associated with heroin/other opioid addiction, despite their biological plausibility. We used evidence of polymorphisms altering OPRM1 expr...

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Bibliografiset tiedot
Julkaisussa:Biol Psychiatry
Päätekijät: Hancock, Dana B., Levy, Joshua L., Gaddis, Nathan C., Glasheen, Cristie, Saccone, Nancy L., Page, Grier P., Hulse, Gary, Wildenauer, Dieter, Kelty, Erin, Schwab, Sibylle, Degenhardt, Louisa, Martin, Nicholas G., Montgomery, Grant W., Attia, John, Holliday, Elizabeth G., McEvoy, Mark, Scott, Rodney J., Bierut, Laura J., Nelson, Elliot C., Kral, Alex, Johnson, Eric O.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519434/
https://ncbi.nlm.nih.gov/pubmed/25744370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.01.003
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